Splicing misplaced
- PMID: 16096050
- DOI: 10.1016/j.cell.2005.07.016
Splicing misplaced
Abstract
Newly synthesized transcripts are usually spliced during transcription or immediately thereafter. So pre-mRNA splicing has been presumed to occur exclusively in the cell nucleus. In this issue of Cell, Denis et al. (2005) now report the presence of functional spliceosomes and signal-dependent pre-mRNA splicing in the cytoplasm of platelets.
Comment on
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Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets.Cell. 2005 Aug 12;122(3):379-91. doi: 10.1016/j.cell.2005.06.015. Cell. 2005. PMID: 16096058 Free PMC article.
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