Review
doi: 10.1016/j.tig.2005.08.001.
The evolution of noncoding DNA: how much junk, how much func?
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- PMID: 16098630
- DOI: 10.1016/j.tig.2005.08.001
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Review
The evolution of noncoding DNA: how much junk, how much func?
Trends Genet.
2005 Oct.
Abstract
Comparative sequence analysis on a genomic scale has opened the door for the systematic analysis of cis-acting regulatory DNA. It is now possible to begin to answer basic questions such as, how much meaningful noncoding sequence is in the genome? How strong is natural selection on functional noncoding sequences in different species? Two recent articles have capitalized on the comparative genomic approach in an attempt to answer these questions with surprising results.
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