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Comment
. 2005 Aug;2(2):80-2.
doi: 10.1016/j.cmet.2005.07.006.

A SIRTain role in pancreatic beta cell function

Ingo B Leibiger  1 , Per-Olof Berggren
Affiliations
Free article
Comment

A SIRTain role in pancreatic beta cell function

Ingo B Leibiger et al. Cell Metab. 2005 Aug.
Free article

Abstract

Genes formerly thought to be involved solely in the regulation of life span have increasingly become implicated in the regulation of metabolic processes. Moynihan et al.(2005[this issue of Cell Metabolism]) now demonstrate that increasing levels of Sirt1 in the pancreatic beta cells of mice result in a more efficient glucose handling due to enhanced glucose-stimulated insulin secretion.

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