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. 2005 Aug;193(2):361-2.
doi: 10.1016/j.ajog.2005.01.025.

Common use of inaccurate antibody assays to identify infection status with herpes simplex virus type 2

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Common use of inaccurate antibody assays to identify infection status with herpes simplex virus type 2

Rhoda Ashley Morrow et al. Am J Obstet Gynecol. 2005 Aug.

Abstract

In recent proficiency testing of herpes simplex virus type-specific serologic evidence by the College of American Pathologists, commercially available herpes simplex virus antibody assays that were not glycoprotein-G based demonstrated high false-positive rates (14%-88%) for herpes simplex virus type-2 antibodies in sera that were positive for herpes simplex virus type-1 antibodies but negative for herpes simplex virus type-2 antibodies. Herpes simplex virus serologic testing should be performed with only glycoprotein-G-based tests.

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