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Review
. 2005;110(2 Suppl 1):183-7.

Growth factors and their receptors: fundamental molecules for human placental development

Affiliations
  • PMID: 16101037
Review

Growth factors and their receptors: fundamental molecules for human placental development

D Marzioni et al. Ital J Anat Embryol. 2005.

Abstract

In this review we present data concerning the localization of some important growth factors and their receptors in the human placenta. We focus our attention on molecules playing a fundamental role in angiogenesis and morphologic processes as beta-FGF, EGF and TGF-beta. The distribution of these growth factors and their receptors in the placental villi during gestation suggests that these molecules play a pivotal role in growth and differentiation of the villous tree.

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