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Comparative Study
. 2005 Aug;44(8):636-40.
doi: 10.1111/j.1365-4632.2004.02027.x.

A comparative study of superoxide dismutase, catalase, and glutathione peroxidase activities and nitrate levels in vitiligo patients

Ersoy Hazneci  1 , Aysun Bay Karabulut, Cetin Oztürk, Kadir Batçioğlu, Gürsoy Doğan, Semsettin Karaca, Muammer Eşrefoğlu
Affiliations
Comparative Study

A comparative study of superoxide dismutase, catalase, and glutathione peroxidase activities and nitrate levels in vitiligo patients

Ersoy Hazneci et al. Int J Dermatol. 2005 Aug.

Abstract

Background: Several groups have shown the involvement of oxidative stress in the pathophysiology of vitiligo.

Methods: In this study, we examined the erythrocyte and plasma activities of glutathione peroxidase and Cu/Zn superoxide dismutase, plasma nitrite/nitrate levels, and erythrocyte catalase activity in 23 vitiligo patients and 25 controls.

Results: The results show that erythrocyte superoxide dismutase activity and plasma nitrite/nitrate levels are high in vitiligo patients.

Conclusions: Our study confirms that oxidative stress is involved in the pathophysiology of vitiligo, as indicated by the high levels of erythrocyte superoxide dismutase activity and plasma nitrite/nitrate.

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