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Multicenter Study
. 2005 Sep 2;19(13):1433-4.
doi: 10.1097/01.aids.0000180791.85003.3b.

Low incidence of hepatotoxicity in a cohort of HIV patients treated with lopinavir/ritonavir

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Multicenter Study

Low incidence of hepatotoxicity in a cohort of HIV patients treated with lopinavir/ritonavir

Paolo Bonfanti et al. AIDS. .

Abstract

We describe the hepatotoxicity encountered in a cohort of HIV-positive patients treated with lopinavir/ritonavir. We used the database from the SCOLTA project, an on-line pharmacovigilance programme involving 25 Italian infectious disease centres. A total of 755 patients were followed, over a mean observation period of 16 months. The incidence of severe events was low despite the high prevalence of patients co-infected with hepatitis virus at enrollment.

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