Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 Sep;22(9):612-6.
doi: 10.1136/emj.2003.009613.

Naloxone in opioid poisoning: walking the tightrope

S F J Clarke  1 , P I Dargan, A L Jones
Affiliations
Review

Naloxone in opioid poisoning: walking the tightrope

S F J Clarke et al. Emerg Med J. 2005 Sep.

Abstract

Acute opioid intoxication and overdose are common causes of presentation to emergency departments. Although naloxone, a pure opioid antagonist, has been available for many years, there is still confusion over the appropriate dose and route of administration. This article looks at the reasons for this uncertainty and undertakes a literature review from which a treatment algorithm is presented.

PubMed Disclaimer

References

    1. Am J Emerg Med. 1994 Nov;12(6):650-60 - PubMed
    1. J Toxicol Clin Toxicol. 1996;34(4):409-16 - PubMed
    1. BMJ. 1996 Aug 24;313(7055):481-2 - PubMed
    1. Acad Emerg Med. 1996 Jul;3(7):660-7 - PubMed
    1. Am J Emerg Med. 1997 Mar;15(2):217-8 - PubMed

MeSH terms