Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 Aug 31;127(34):11934-5.
doi: 10.1021/ja053458f.

An air-stable P-chiral phosphine ligand for highly enantioselective transition-metal-catalyzed reactions

Tsuneo Imamoto  1 , Keitaro Sugita, Kazuhiro Yoshida
Affiliations

An air-stable P-chiral phosphine ligand for highly enantioselective transition-metal-catalyzed reactions

Tsuneo Imamoto et al. J Am Chem Soc. .

Abstract

A new P-chiral phosphine ligand, (R,R)-2,3-bis(tert-butylmethylphosphino)quinoxaline, has been prepared by the reaction of enantiomerically pure tert-butylmethylphosphine-borane with 2,3-dichloroquinoxaline. This ligand, in contrast to most of the previously reported P-chiral ligands, is an air-stable solid and exhibits excellent enantioselectivities in both Rh-catalyzed asymmetric hydrogenations and Rh- or Pd-catalyzed carbon-carbon bond-forming reactions.

PubMed Disclaimer

LinkOut - more resources