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. 2005 Aug 22;167(34):3189-91.

[Selective reporting of positive outcomes in randomised trials--secondary publication.. A comparison of protocols with published reports]

[Article in Danish]
Asbjørn Hróbjartsson  1 , An-Wen Chan, Mette T Haahr, Peter C Gøtzsche, Douglas G Altman
Affiliations
  • PMID: 16117920

[Selective reporting of positive outcomes in randomised trials--secondary publication.. A comparison of protocols with published reports]

[Article in Danish]
Asbjørn Hróbjartsson et al. Ugeskr Laeger. .

Abstract

Introduction: Selective reporting of positive outcomes is associated with bias.

Materials and methods: We conducted a cohort study of 102 protocols of randomised trials approved by the Scientific Ethics Committees for Copenhagen and Frederiksberg in 1994-1995 and the corresponding 122 reports.

Results: The median proportion of incompletely reported outcomes per trial was 50%. Statistically significant outcomes were more often fully reported, odds ratio 2.4. In 62% of trials, at least one primary outcome was changed.

Discussion: Outcomes in randomised trials are often reported selectively.

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