Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 Sep 1;7(18):4009-11.
doi: 10.1021/ol051654l.

Ruthenium-catalyzed arylation of 2-alkenylpyridines with aryl bromides: alternative E,Z-selectivity to Mizoroki-Heck reaction

Shuichi Oi  1 , Kaori Sakai, Yoshio Inoue
Affiliations

Ruthenium-catalyzed arylation of 2-alkenylpyridines with aryl bromides: alternative E,Z-selectivity to Mizoroki-Heck reaction

Shuichi Oi et al. Org Lett. .

Abstract

Regio- and stereoselective arylation of 2-alkenylpyridines with aryl bromides is catalyzed by specific Ru(II)-phosphine complexes affording beta-arylated (Z)-2-alkenylpyridines, in which the aryl moiety is introduced cis to the pyridyl group. This geometrical selectivity is in sharp contrast to the Mizoroki-Heck reaction. [reaction: see text]

PubMed Disclaimer

LinkOut - more resources