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Case Reports
. 2006 Feb;70(2):365-70.
doi: 10.1016/j.ijporl.2005.07.009. Epub 2005 Aug 25.

Agenesis of the trachea: phenotypic expression of a rare cause of fatal neonatal respiratory insufficiency in six patients

Janine F Felix  1 , Marjolein A J van Looij, Ralph V Pruijsten, Ronald R de Krijger, Annelies de Klein, Dick Tibboel, Hans L J Hoeve
Affiliations
Case Reports

Agenesis of the trachea: phenotypic expression of a rare cause of fatal neonatal respiratory insufficiency in six patients

Janine F Felix et al. Int J Pediatr Otorhinolaryngol. 2006 Feb.

Abstract

Tracheal agenesis is a rare congenital malformation, which is usually fatal in the newborn period. Its incidence is approximately 1 in 50,000 births. Presentation is with respiratory insufficiency and no audible cry. Other anomalies are found in most cases. Six cases of tracheal agenesis were seen in our hospital since 1988. Their medical records were reviewed. Three of our cases classify as Floyd's type III, two as Floyd's type II and one as Floyd's type I. Associated anomalies were found in five cases. The classification of tracheal agenesis, associated anomalies and potential therapeutic options are discussed.

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