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Randomized Controlled Trial
. 2005 Sep;19(9):1172-6.
doi: 10.1007/s00464-004-8207-4. Epub 2005 Jul 28.

Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer

H Hayashi  1 , T Ochiai, H Shimada, Y Gunji
Affiliations
Randomized Controlled Trial

Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer

H Hayashi et al. Surg Endosc. 2005 Sep.

Abstract

Background: Laparoscopy-assisted surgery with extraperigastric lymph node dissection for gastric cancers has been described, but the clinical benefits of these surgeries still are unclear. Short-term clinical outcomes were compared between laparoscopy-assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) for early gastric cancer in a prospective randomized fashion.

Methods: For this study, 28 patients with early gastric cancers in the lower half of the stomach were randomly assigned to either LADG (n = 4) or ODG (n = 14). Postoperative pain, levels of acute inflammatory responses, and pathologic evaluation of the operative specimens were compared.

Results: The LADG group required a significantly shorter period of postoperative epidural anesthesia, showed significantly lower levels of serum interleukin-6 and C-reactive protein, and had no major postsurgery complications. Pathologic examinations showed that surgery was equally radical in the two groups.

Conclusion: The findings show that LADG with extraperigastric lymph node dissection is a safe and less invasive alternative to the open procedure.

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