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Review
. 2005 Sep 6;15(17):R661-3.
doi: 10.1016/j.cub.2005.08.025.

Chaperomics: in vivo GroEL function defined

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Free article
Review

Chaperomics: in vivo GroEL function defined

R John Ellis. Curr Biol. .
Free article

Abstract

A recent proteome analysis of protein folding inside cells of Escherichia coli predicts that only 84 of the approximately 2400 cytosolic proteins expressed in minimal media depend absolutely on the GroEL/GroES chaperone system to avoid aggregation. These proteins are enriched in alpha/beta domains and 13 are essential for growth.

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