Chaperomics: in vivo GroEL function defined
- PMID: 16139196
- DOI: 10.1016/j.cub.2005.08.025
Chaperomics: in vivo GroEL function defined
Abstract
A recent proteome analysis of protein folding inside cells of Escherichia coli predicts that only 84 of the approximately 2400 cytosolic proteins expressed in minimal media depend absolutely on the GroEL/GroES chaperone system to avoid aggregation. These proteins are enriched in alpha/beta domains and 13 are essential for growth.
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