Review
doi: 10.1016/j.ccm.2005.05.008.
The lung in space
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- PMID: 16140136
- DOI: 10.1016/j.ccm.2005.05.008
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Review
The lung in space
Clin Chest Med.
2005 Sep.
Abstract
The lung is exquisitely sensitive to gravity, which induces gradients in ventilation, blood flow, and gas exchange. Studies of lungs in microgravity provide a means of elucidating the effects of gravity. They suggest a mechanism by which gravity serves to match ventilation to perfusion, making for a more efficient lung than anticipated. Despite predictions, lungs do not become edematous, and there is no disruption to, gas exchange in microgravity. Sleep disturbances in microgravity are not a result of respiratory-related events; obstructive sleep apnea is caused principally by the gravitational effects on the upper airways. In microgravity, lungs may be at greater risk to the effects of inhaled aerosols.
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