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Review
. 2005 Sep;79(18):11555-8.
doi: 10.1128/JVI.79.18.11555-11558.2005.

Adaptive value of high mutation rates of RNA viruses: separating causes from consequences

Santiago F Elena  1 , Rafael Sanjuán
Affiliations
Review

Adaptive value of high mutation rates of RNA viruses: separating causes from consequences

Santiago F Elena et al. J Virol. 2005 Sep.
No abstract available

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References

    1. Back, N., M. Nijhuis, W. Keulen, C. Boucher, B. Oude Essink, A. van Kuilenburg, A. van Gennip, and B. Berkhout. 1996. Reduced replication of 3TC resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. EMBO J. 15:4040-4049. - PMC - PubMed
    1. Bonhoeffer, S., C. Chappey, N. T. Parkin, J. M. Whitcomb, and C. J. Petropoulos. 2004. Evidence for positive epistasis in HIV-1. Science 306:1547-1550. - PubMed
    1. Bonhoeffer, S., and P. Sniegowski. 2002. The importance of being erroneous. Nature 420:367-368. - PubMed
    1. Bordería, A. V., and S. F. Elena. 2002. r- and K-selection in experimental populations of vesicular stomatitis virus. Infect. Genet. Evol. 2:137-143. - PubMed
    1. Burch, C. L., and L. Chao. 2000. Evolvability of an RNA virus is determined by its mutational neighbourhood. Nature 406:625-628. - PubMed

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