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. 2005 Oct 1;41(7):1045-8.
doi: 10.1086/433180. Epub 2005 Aug 22.

Undetectable plasma HIV RNA load predicts success after hepatitis B vaccination in HIV-infected persons

Edgar Turner Overton  1 , Somnuek Sungkanuparph, William G Powderly, Warren Seyfried, Richard K Groger, Judith A Aberg
Affiliations

Undetectable plasma HIV RNA load predicts success after hepatitis B vaccination in HIV-infected persons

Edgar Turner Overton et al. Clin Infect Dis. .

Abstract

Human immunodeficiency virus (HIV)-infected patients respond poorly to hepatitis B vaccination. Records of 194 HIV-infected patients were reviewed for factors associated with successful hepatitis B vaccination. Thirty-four patients (17.5%) developed a protective antibody response. In a logistic regression model, only a plasma HIV RNA level of <400 copies/mL at the time of vaccination was associated with a protective antibody response (P=.003).

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