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Case Reports
. 2005 Oct 1;41(7):1049-52.
doi: 10.1086/433177. Epub 2005 Aug 30.

Immune reconstitution syndrome due to bacillus Calmette-Guérin after initiation of antiretroviral therapy in children with HIV infection

Thanyawee Puthanakit  1 , Penninah Oberdorfer, Suchart Punjaisee, Pornphun Wannarit, Thira Sirisanthana, Virat Sirisanthana
Affiliations
Case Reports

Immune reconstitution syndrome due to bacillus Calmette-Guérin after initiation of antiretroviral therapy in children with HIV infection

Thanyawee Puthanakit et al. Clin Infect Dis. .

Abstract

The immune reconstitution syndrome caused by bacillus Calmette-Guerin (BCG) was found in 4 HIV-infected children who were immunized with BCG at birth. The localized, suppurative, BCG-related complications developed within 10 weeks after initiation of antiretroviral therapy. The incidence rate was 2.7 cases per 100 persons (95% confidence interval, 0.7-6.7). Patients responded well to treatment with isoniazid and rifampicin.

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Figures

Figure 1
Figure 1
A, A photograph of severe suppurative axillary lymphadenitis 4 weeks after the commencement of combination antiretroviral therapy. B, A photograph of an abscess at a bacillus Calmette-Guérin (BCG) vaccination site with ipsilateral axillary lymphadenopathy 4 weeks after the commencement of combination antiretroviral therapy.
See this image and copyright information in PMC

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