Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2005 Aug;98(8):811-3.
doi: 10.1097/01.SMJ.0000163315.02563.B2.

Two probable cases of serious drug interaction between clarithromycin and colchicine

Vincent C C Cheng  1 , P L Ho, K Y Yuen
Affiliations
Case Reports

Two probable cases of serious drug interaction between clarithromycin and colchicine

Vincent C C Cheng et al. South Med J. 2005 Aug.

Abstract

Although colchicine is a commonly used medication in patients with gouty arthritis and various multisystem disorders, its safety margin in therapeutic use is not well understood. This report describes two fatal cases of agranulocytosis presumed to result from a drug interaction involving colchicine and clarithromycin.

PubMed Disclaimer

Publication types