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Comparative Study
. 2005 Sep;43(9):4823-5.
doi: 10.1128/JCM.43.9.4823-4825.2005.

PCR-based diagnosis of neonatal staphylococcal bacteremias

Affiliations
Comparative Study

PCR-based diagnosis of neonatal staphylococcal bacteremias

Imad R Makhoul et al. J Clin Microbiol. 2005 Sep.

Abstract

We compared PCR with blood cultures in the diagnosis of neonatal staphylococcal sepsis. Significant association was observed between PCR-based and culture-based diagnosis of staphylococcal bacteremia. Positive and negative predictive values for PCR were 100% and 98%, respectively. These data indicate that PCR may serve as a useful adjunct for the rapid diagnosis of staphylococcal sepsis.

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References

    1. Briones, C. R., M. E. Villanueva-Uy, and H. G. Uy. 2003. The use of polymerase chain reaction in neonatal candidemia. Pediatr. Res. 53:396A. - PubMed
    1. Jaffe, R. I., J. D. Lane, S. V. Albury, and D. M. Niemeyer. 2000. Rapid extraction from and direct identification in clinical samples of methicillin-resistant staphylococci using the PCR. J. Clin. Microbiol. 38:3407-3412. - PMC - PubMed
    1. Jordan, J. A., and M. B. Durso. 2000. Comparison of 16S rRNA gene PCR and BACTEC 9240 for detection of neonatal bacteremia. J. Clin. Microbiol. 38:2574-2578. - PMC - PubMed
    1. Karlowicz, M. G., E. S. Buescher, and A. E. Surka. 2000. Fulminant late-onset sepsis in a neonatal intensive care unit, 1988-1997, and the impact of avoiding empiric vancomycin therapy. Pediatrics 106:1387-1390. - PubMed
    1. Kellogg, J. A., J. P. Manzella, and D. A. Bankert. 2000. Frequency of low-level bacteremia in children from birth to fifteen years of age. J. Clin. Microbiol. 38:2181-2185. - PMC - PubMed

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