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. 2005 Sep;43(9):4889-90.
doi: 10.1128/JCM.43.9.4889-4890.2005.

Use of paired serum samples for serodiagnosis of typhoid fever

Deborah House  1 , Nguyen T Chinh, To S Diep, Christopher M Parry, John Wain, Gordon Dougan, Nicholas J White, Tran Tinh Hien, Jeremy J Farrar
Affiliations

Use of paired serum samples for serodiagnosis of typhoid fever

Deborah House et al. J Clin Microbiol. 2005 Sep.

Abstract

Using an enzyme-linked immunosorbent assay we demonstrate that, in adult patients with typhoid fever, the sensitivity of a serological test based on the detection of anti-lipopolysaccharide immunoglobulin G is increased when used with paired serum samples taken 1 week apart.

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Figures

FIG. 1.
FIG. 1.
Serum anti-LPS IgG (a) and anti-flagella IgG (b) titers for adult patients with nonsevere typhoid fever. Samples were collected immediately before (day 1), during (day 4), and after (day 7) treatment. Points below the dashed line indicate a titer of <1/50. The median titer for each day is shown by a solid, black horizontal line.
See this image and copyright information in PMC

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