Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 Sep;43(9):4902-4.
doi: 10.1128/JCM.43.9.4902-4904.2005.

Breakthrough disseminated Aspergillus ustus infection in allogeneic hematopoietic stem cell transplant recipients receiving voriconazole or caspofungin prophylaxis

Juliette Pavie  1 , Claire Lacroix, Dea Garcia Hermoso, Marie Robin, Christèle Ferry, Anne Bergeron, Martine Feuilhade, Françoise Dromer, Eliane Gluckman, Jean-Michel Molina, Patricia Ribaud
Affiliations
Review

Breakthrough disseminated Aspergillus ustus infection in allogeneic hematopoietic stem cell transplant recipients receiving voriconazole or caspofungin prophylaxis

Juliette Pavie et al. J Clin Microbiol. 2005 Sep.

Abstract

Aspergillus ustus is an uncommon clinical species which is poorly susceptible to antifungals. We report two cases of A. ustus infections that occurred in allogeneic stem cell transplant recipients while they were receiving either voriconazole or caspofungin. Prolonged use of these new antifungal agents may increase the risk of the emergence of resistant organisms.

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Left panel: pigmented and smooth-walled conidiophore stipe of A. ustus with spherical vesicle and biseriate conidiogenous cells. Spherical conidia with very rough walls (magnification, ×1,000). Right panel: irregular Hülle cells of A. ustus (magnification, ×1,000).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Arikan, S., M. Lozano-Chiu, V. Paetznick, and J. H. Rex. 2001. In vitro susceptibility testing methods for caspofungin against Aspergillus and Fusarium isolates. Antimicrob. Agents Chemother. 45:327-330. - PMC - PubMed
    1. Ascioglu, S., J. H. Rex, B. de Pauw, J. E. Bennett, J. Bille, F. Crokaert, D. W. Denning, J. P. Donnelly, J. E. Edwards, Z. Erjavec, D. Fiere, O. Lortholary, J. Maertens, J. F. Meis, T. F. Patterson, J. Ritter, D. Selleslag, P. M. Shah, D. A. Stevens, and T. J. Walsh. 2002. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin. Infect. Dis. 34:7-14. - PubMed
    1. Azzola, A., J. R. Passweg, J. M. Habicht, L. Bubendorf, M. Tamm, A. Gratwohl, and G. Eich. 2004. Use of lung resection and voriconazole for successful treatment of invasive pulmonary Aspergillus ustus infection. J. Clin. Microbiol. 42:4805-4808. - PMC - PubMed
    1. Baddley, J. W., T. P. Stroud, D. Salzman, and P. G. Pappas. 2001. Invasive mold infections in allogeneic bone marrow transplant recipients. Clin. Infect. Dis. 32:1319-1324. - PubMed
    1. Bretagne, S., A. Marmorat-Khuong, M. Kuentz, J. P. Latge, E. Bart-Delabesse, and C. Cordonnier. 1997. Serum Aspergillus galactomannan antigen testing by sandwich ELISA: practical use in neutropenic patients. J. Infect. 35:7-15. - PubMed

MeSH terms