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Review
. 2005 Sep;43(9):4902-4.
doi: 10.1128/JCM.43.9.4902-4904.2005.

Breakthrough disseminated Aspergillus ustus infection in allogeneic hematopoietic stem cell transplant recipients receiving voriconazole or caspofungin prophylaxis

Juliette Pavie  1 , Claire Lacroix, Dea Garcia Hermoso, Marie Robin, Christèle Ferry, Anne Bergeron, Martine Feuilhade, Françoise Dromer, Eliane Gluckman, Jean-Michel Molina, Patricia Ribaud
Affiliations
Review

Breakthrough disseminated Aspergillus ustus infection in allogeneic hematopoietic stem cell transplant recipients receiving voriconazole or caspofungin prophylaxis

Juliette Pavie et al. J Clin Microbiol. 2005 Sep.

Abstract

Aspergillus ustus is an uncommon clinical species which is poorly susceptible to antifungals. We report two cases of A. ustus infections that occurred in allogeneic stem cell transplant recipients while they were receiving either voriconazole or caspofungin. Prolonged use of these new antifungal agents may increase the risk of the emergence of resistant organisms.

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Figures

FIG. 1.
FIG. 1.
Left panel: pigmented and smooth-walled conidiophore stipe of A. ustus with spherical vesicle and biseriate conidiogenous cells. Spherical conidia with very rough walls (magnification, ×1,000). Right panel: irregular Hülle cells of A. ustus (magnification, ×1,000).
See this image and copyright information in PMC

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