GABA receptors gone bad: the wrong place at the wrong time
- PMID: 16145612
- PMCID: PMC1198625
- DOI: 10.1111/j.1535-7511.2005.05304.x
GABA receptors gone bad: the wrong place at the wrong time
Comment on
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Altered expression of the delta subunit of the GABAA receptor in a mouse model of temporal lobe epilepsy.J Neurosci. 2004 Sep 29;24(39):8629-39. doi: 10.1523/JNEUROSCI.2877-04.2004. J Neurosci. 2004. PMID: 15456836 Free PMC article.
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The GABAA receptor gamma2 subunit R43Q mutation linked to childhood absence epilepsy and febrile seizures causes retention of alpha1beta2gamma2S receptors in the endoplasmic reticulum.J Neurosci. 2004 Oct 6;24(40):8672-7. doi: 10.1523/JNEUROSCI.2717-04.2004. J Neurosci. 2004. PMID: 15470132 Free PMC article.
References
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- Wallace RH, Marini C, Petrou S, Harkin LA, Bowser DN, Panchal RG, Williams DA, Sutherland GR, Mulley JC, Scheffer IE, Berkovic SF. Mutant GABA(A) receptor gamma2-subunit in childhood absence epilepsy and febrile seizures. Nat Genet. 2001;28:49–52. - PubMed
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- Sancar F, Czajkowski C. A GABAA receptor mutation linked to human epilepsy (gamma2R43Q) impairs cell surface expression of alphabetagamma receptors. J Biol Chem. 2004;279:47034–47039. - PubMed
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- Luscher B, Keller CA. Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses. Pharmacol Ther. 2004;102:195–221. - PubMed
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