No phobias about PhoB activation
- PMID: 16154079
- DOI: 10.1016/j.str.2005.08.002
No phobias about PhoB activation
Abstract
Structures of the inactive and activated forms of the receiver domain of PhoB reported in this issue of Structure (Bachhawat et al., 2005) suggest that the OmpR/PhoB subclass of transcription factors becomes active by dimerization about a symmetric axis utilizing the alpha4-beta5-alpha5 surface.
Comment on
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Mechanism of activation for transcription factor PhoB suggested by different modes of dimerization in the inactive and active states.Structure. 2005 Sep;13(9):1353-63. doi: 10.1016/j.str.2005.06.006. Structure. 2005. PMID: 16154092 Free PMC article.
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