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Clinical Trial
. 2005 Sep 13;65(5):765-7.
doi: 10.1212/01.wnl.0000174433.76707.8c.

Autonomic function after botulinum toxin type A or B: a double-blind, randomized trial

R Tintner  1 , R Gross, U F Winzer, K A Smalky, J Jankovic
Affiliations
Clinical Trial

Autonomic function after botulinum toxin type A or B: a double-blind, randomized trial

R Tintner et al. Neurology. .

Abstract

To compare autonomic effects of botulinum toxin (BTX), we randomized patients with cervical dystonia to receive either BTX-A or BTX-B in a double-blind manner. Efficacy and physiologic questionnaire measures of autonomic function were assessed at baseline and 2 weeks after injection. Patients treated with BTX-B had less saliva production (p < 0.01) and greater severity of constipation (p = 0.037) than those treated with BTX-A, but did not differ in other tests of autonomic functions.

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