Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Feb;92(2):155-61.
doi: 10.1136/hrt.2005.066944. Epub 2005 Sep 13.

Antithrombotic treatment in atrial fibrillation

G Y H Lip  1 , C J Boos
Affiliations
Review

Antithrombotic treatment in atrial fibrillation

G Y H Lip et al. Heart. 2006 Feb.

Abstract

Atrial fibrillation (AF) is the most common sustained arrhythmia, that substantially increases morbidity and mortality. AF is gaining in clinical and economic importance, with stroke and thromboembolism being major complications. In this article, the evidence for AF treatment trial of antithrombotic therapy is reviewed. Stroke risk stratification of patients with AF is discussed, and practical recommendations for thromboprophylaxis are presented.

PubMed Disclaimer

Conflict of interest statement

Competing interests: GL has received funding for research, educational symposia, consultancy and lecturing from different manufacturers of drugs used for the treatment of atrial fibrillation and thrombosis. He is Clinical Adviser to the Guideline Development Group writing the United Kingdom National Institute of Clinical Excellence (NICE) Guidelines on atrial fibrillation management (www.nice.org.uk).

References

    1. Fuster V, Ryden L E, Asinger R W.et al ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary a report of the American College of Cardiology/American Heart Association task force on practice guidelines and the European Society of Cardiology committee for practice guidelines and policy conferences (committee to develop guidelines for the management of patients with atrial fibrillation) developed in collaboration with the North American Society of Pacing and Electrophysiology. Circulation 20011042118–2150. - PubMed
    1. Singer D E, Albers G W, Dalen J E.et al Antithrombotic therapy in atrial fibrillation: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004126(suppl)429S–56S. - PubMed
    1. Stewart S, Murphy N, Walker A.et al Cost of an emerging epidemic: an economic analysis of atrial fibrillation in the UK Heart 200490286–292. - PMC - PubMed
    1. Freestone B, Lip G Y H. Epidemiology and costs of cardiac arrhythmias. In: Lip GYH, Godtfredsen J, eds. Cardiac arrhythmias: a clinical approach. Edinburgh: Mosby, 20033–24.
    1. Go A S, Hylek E M, Phillips K A.et al Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study.JAMA 20012852370–2375. - PubMed

Substances