The mechanism of inhibition on the endogenous respiration of Ehrlich ascites tumor cells by the cyanine dye diS-C3-(5)
- PMID: 161623
The mechanism of inhibition on the endogenous respiration of Ehrlich ascites tumor cells by the cyanine dye diS-C3-(5)
Abstract
The cyanine dye 3,3'-dipropyl-2,2'-thiadicarbocyanine iodide [diS-C3(5)] was found to be a potent inhibitor of endogenous respiration of Ehrlich ascites tumor cells. This effect is believed to involve both rotenone and uncoupler type actions of the dye on the electron transport system of the mitochondria.
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