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Comparative Study
. 2005 Sep;84(3):761-5.
doi: 10.1016/j.fertnstert.2005.04.021.

Plasminogen activator inhibitor 1 and miscarriage after metformin treatment and laparoscopic ovarian drilling in patients with polycystic ovary syndrome

Stefano Palomba  1 , Francesco Orio Jr, Angela Falbo, Tiziana Russo, Achille Tolino, Fulvio Zullo
Affiliations
Free article
Comparative Study

Plasminogen activator inhibitor 1 and miscarriage after metformin treatment and laparoscopic ovarian drilling in patients with polycystic ovary syndrome

Stefano Palomba et al. Fertil Steril. 2005 Sep.
Free article

Abstract

In women with polycystic ovary syndrome, metformin administration, not laparoscopic ovarian drilling, reduces plasminogen activator inhibitor 1 (PAI-1) activity. The lack of a decrease in PAI-1 activity is related to a high risk for miscarriage.

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