Review
doi: 10.1152/physiol.00019.2005.
Molecular pathways leading to cancer cachexia
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- PMID: 16174873
- DOI: 10.1152/physiol.00019.2005
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Review
Molecular pathways leading to cancer cachexia
Physiology (Bethesda).
2005 Oct.
Free article
Abstract
Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue.
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