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Review
. 2005 Oct:20:340-8.
doi: 10.1152/physiol.00019.2005.

Molecular pathways leading to cancer cachexia

Michael J Tisdale  1
Affiliations
Free article
Review

Molecular pathways leading to cancer cachexia

Michael J Tisdale. Physiology (Bethesda). 2005 Oct.
Free article

Abstract

Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue.

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