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Review
. 2004;1(1):5-18.
doi: 10.1385/ncc:1:1:5.

Intracerebral hemorrhage: pathophysiology and therapy

Guohua Xi  1 , Matthew E Fewel, Ya Hua, B Gregory Thompson Jr, Julian T Hoff, Richard F Keep
Affiliations
Review

Intracerebral hemorrhage: pathophysiology and therapy

Guohua Xi et al. Neurocrit Care. 2004.

Abstract

Spontaneous intracerebral hemorrhage, from several sources, causes instantaneous mass effect, disruption of surrounding brain, and often an early neurological death. If the patient survives the initial event, the hematoma can lead to secondary brain injury, neurological deficits, and, occasionally, delayed fatality. The mechanisms that trigger pathophysiological changes in and around the hematoma are becoming better understood, offering new therapeutic opportunities.

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