Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC
- PMID: 16176645
- DOI: 10.1093/chromsci/43.7.348
Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC
Abstract
The present work describes the isolation of camptothecin and 9-methoxycamptothecin from the aerial parts of Nothapodytes foetida by semipreparative high-performance liquid chromatography because the separation of compounds by conventional procedures is tedious and cumbersome. The purity of the isolates is determined by physicochemical data and liquid chromatography-mass spectrometry.
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