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. 2005 Aug;43(7):348-50.
doi: 10.1093/chromsci/43.7.348.

Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC

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Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC

S C Puri et al. J Chromatogr Sci. 2005 Aug.

Abstract

The present work describes the isolation of camptothecin and 9-methoxycamptothecin from the aerial parts of Nothapodytes foetida by semipreparative high-performance liquid chromatography because the separation of compounds by conventional procedures is tedious and cumbersome. The purity of the isolates is determined by physicochemical data and liquid chromatography-mass spectrometry.

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