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Case Reports
. 2005 Apr;49(2):323-7.
doi: 10.1590/s0004-27302005000200023. Epub 2005 Sep 12.

Duplication of the hypophysis associated with precocious puberty: presentation of two cases and review of pituitary embryogenesis

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Case Reports

Duplication of the hypophysis associated with precocious puberty: presentation of two cases and review of pituitary embryogenesis

Gustavo Cancela de Penna et al. Arq Bras Endocrinol Metabol. 2005 Apr.

Abstract

Pituitary duplication is a rare malformation commonly associated with other major neural/craniofacial anomalies, easily shown by magnetic resonance imaging. The authors describe two girls with duplication of the pituitary gland and thickening of the hypothalamus, facial dysmorphism and precocious pubertal development. The pathogenesis of pituitary duplication and its relationship with precocious pubertal development are discussed.

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