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Comment
. 2005 Oct 4;102(40):14127-8.
doi: 10.1073/pnas.0507119102. Epub 2005 Sep 26.

Effects of ionizing radiation in nonirradiated cells

William F Morgan  1 , Marianne B Sowa
Affiliations
Comment

Effects of ionizing radiation in nonirradiated cells

William F Morgan et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Fig. 1.
Fig. 1.
Ionizing radiation induces direct DNA damage and indirect damage through the radiolysis of water. This damage is either eliminated or fixed in the cell as a mutation or chromosomal rearrangement by DNA repair processes. After release by cell cycle checkpoint control mechanisms, an irradiated surviving cell (blue) may proliferate, passing on the legacy of radiation to its progeny (diagram A), potentially initiating the carcinogenic process. The irradiated cell (blue) can also communicate with nonirradiated neighboring cells (cyan) by cell-to-cell gap junction communication and/or secretion of soluble factors eliciting nontargeted apoptosis (black) or micronucleation (red) in cells that have never been exposed to radiation (diagram B).
See this image and copyright information in PMC

Comment on

References

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