Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005:61 Suppl 7:128-134.
doi: 10.1002/prot.20729.

Free modeling with Rosetta in CASP6

Philip Bradley  1 , Lars Malmström  1 , Bin Qian  1 , Jack Schonbrun  1 , Dylan Chivian  1 , David E Kim  1 , Jens Meiler  2 , Kira M S Misura  1 , David Baker  1
Affiliations

Free modeling with Rosetta in CASP6

Philip Bradley et al. Proteins. 2005.

Abstract

We describe Rosetta predictions in the Sixth Community-Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction (CASP), focusing on the free modeling category. Methods developed since CASP5 are described, and their application to selected targets is discussed. Highlights include improved performance on larger proteins (100-200 residues) and the prediction of a 70-residue alpha-beta protein to near-atomic resolution.

PubMed Disclaimer

References

REFERENCES

    1. Ginalski K, Elofsson A, Fischer D, Rychlewski L. 3D-Jury: a simple approach to improve protein structure predictions. Bioinformatics 2003; 19: 1015-1018.
    1. Bujnicki JM, Elofsson A, Fischer D, Rychlewski L. Structure prediction meta server. Bioinformatics 2001; 17: 750-751.
    1. Chivian D, Kim DE, Malmstrom L, Bradley P, Robertson T, Murphy P, Strauss CE, Bonneau R, Rohl CA, Baker D. Automated prediction of CASP-5 structures using the Robetta server. Proteins 2003; 53(Suppl 6): 524-533.
    1. Bateman A, Coin L, Durbin R, Finn RD, Hollich V, Griffiths-Jones S, Khanna A, Marshall M, Moxon S, Sonnhammer EL, Studholme DJ, Yeats C, Eddy SR. The Pfam protein families database. Nucleic Acids Res 2004; 32 (Database issue): D138-141.
    1. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997; 25: 3389-3402.

Publication types

LinkOut - more resources