Failure to control prepotent pathways in early stage dementia of the Alzheimer's type: evidence from dichotic listening

Abstract

The authors examined the right ear advantage in a dichotic listening task in healthy aging and very mild and mild stages of Alzheimer's disease. Subjects were simultaneously presented 3 pairs of digits to the left and right ears (e.g., left ear: 4, 3, 1; right ear: 9, 2, 5) for immediate ordered recall. Four lists of triads were presented, varying in presentation rate between digit pairs within a triad (0.5, 1.0, 1.5, 2.0 s). Results indicated that the very mild and mild Alzheimer's groups showed a larger right ear advantage in free recall compared with the healthy controls, indicating a tendency to respond to the prepotent left hemisphere pathway for language processing. Also, the right ear advantage and proportion of switches made during recall were correlated with psychometric measures of frontal lobe function in the mild Alzheimer's group but not in the very mild or healthy control groups.