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Review
. 2005 Sep;1(4):e42.
doi: 10.1371/journal.pcbi.0010042.

The human connectome: A structural description of the human brain

Olaf Sporns  1 , Giulio Tononi, Rolf Kötter
Affiliations
Review

The human connectome: A structural description of the human brain

Olaf Sporns et al. PLoS Comput Biol. 2005 Sep.

Abstract

The connection matrix of the human brain (the human "connectome") represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.

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References

    1. Kötter R. Neuroscience databases: Tools for exploring brain structure function relationships. Phil Trans R Soc Lond B Biol Sci. 2001;356:1111–1120. - PMC - PubMed
    1. Amari S, Arbib MA, Kötter R. Special issue: Neuroinformatics. Neural Netw. 2003;16:1235–1398.
    1. Koslow SH, Subramanian S. Databasing the brain: From data to knowledge. Hoboken (New Jersey): Wiley; 2005. 466. p.
    1. Insel TR, Volkow ND, Li TK, Battey JF, Landis SC. Neuroscience networks: Data sharing in an information age. PLoS Biol. 2003;1:e17. DOI: 10.1371/journal.pbio.0000017. - DOI - PMC - PubMed
    1. Frackowiak RSJ, Friston KJ, Frith C, Dolan R, Price CJ, et al., editors. Human brain function, 2nd ed. New York: Academic Press; 2003. 1,144 p.

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