[Sensory innervation of the brain (primary interoceptive brain neurons and their asynaptic dendrites)]

Abstract

This paper summarizes the author's personal research and the literature data on the sensory innervation of the brain. The following cells were analyzed as presumable primary sensory neurons: ciliated brain neurons, supraependymal plexus and cerebrospinal fluid-contacting intraependymal neurons, Cajal-Retzius neurons of the marginal layer of the cerebral cortex, brain and spinal cord Dolgo-Saburov paravasal neurons, Lugaro cells of the cerebellar cortex, some NO- and synthase-positive cells of the cerebral cortex, asynaptic dendrites of which innervate the precapillary space. Due to the painlessness of the brain and visceral parenchyma, containing local primary sensory neurons, similar to intramural metasympathetic type II Dogiel sensory cells, the hypothesis is formulated on the participation of brain and other intraorgan tissue receptors in the short "autonomic" reflex arcs, which provide only for the local metabolism control, but not for the pain reactions.