MARCKS for maintenance in dendritic spines
- PMID: 16202702
- DOI: 10.1016/j.neuron.2005.09.013
MARCKS for maintenance in dendritic spines
Abstract
Synapses in the brain must maintain a balance between learning-related plasticity and the stability necessary for reliable function. In this issue of Neuron, Calabrese and Halpain describe cell-transfection experiments implicating MARCKS, a protein that binds to both the cell surface and actin cytoskeleton, in the maintenance of dendritic spines.
Comment on
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Essential role for the PKC target MARCKS in maintaining dendritic spine morphology.Neuron. 2005 Oct 6;48(1):77-90. doi: 10.1016/j.neuron.2005.08.027. Neuron. 2005. PMID: 16202710
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