Opioids for non-operable osteoarthritis and soft-tissue rheumatism
- PMID: 16207348
- PMCID: PMC1257452
- DOI: 10.1186/ar1817
Opioids for non-operable osteoarthritis and soft-tissue rheumatism
Abstract
Reviews of oral opioid trials have shown that many side-effects need to be considered when treating patients with non-operable osteoarthritis and soft-tissue problems. European and American guidelines recommend their use with or without paracetamol. The controversy surrounding the use of non-steroidal anti-inflammatory drugs/cyclo-oxygenase-2 inhibitors is limiting physician and patient choices. There is a great need for alternative medication or ways of using current compounds.
Comment on
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Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids.Arthritis Res Ther. 2005;7(5):R1046-51. doi: 10.1186/ar1782. Epub 2005 Jun 28. Arthritis Res Ther. 2005. PMID: 16207320 Free PMC article.
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