Comparative nucleotide sequence analysis of polymorphic variable-number tandem-repeat Loci in Mycobacterium ulcerans
- PMID: 16207997
- PMCID: PMC1248468
- DOI: 10.1128/JCM.43.10.5281-5284.2005
Comparative nucleotide sequence analysis of polymorphic variable-number tandem-repeat Loci in Mycobacterium ulcerans
Abstract
We analyzed a set of variable-number tandem-repeat (VNTR) loci to assess their nucleotide sequence diversity in isolates of three Mycobacterium ulcerans genotypes. Sequence variants in two loci resulted in intraspecies resolution of Southeast Asian and Asian genotypes in contrast to a homogenous sequence composition among African isolates. Nucleotide sequence polymorphism in repeat units can enhance discrimination of VNTR loci.
Similar articles
-
Genotyping Mycobacterium ulcerans and Mycobacterium marinum by using mycobacterial interspersed repetitive units.J Bacteriol. 2005 Mar;187(5):1639-47. doi: 10.1128/JB.187.5.1639-1647.2005. J Bacteriol. 2005. PMID: 15716434 Free PMC article.
-
Multilocus variable-number tandem repeat typing of Mycobacterium ulcerans.J Clin Microbiol. 2005 Apr;43(4):1546-51. doi: 10.1128/JCM.43.4.1546-1551.2005. J Clin Microbiol. 2005. PMID: 15814964 Free PMC article.
-
Identification of a new variable number tandem repeat locus in Mycobacterium ulcerans for potential strain discrimination among African isolates.Clin Microbiol Infect. 2007 Jul;13(7):734-6. doi: 10.1111/j.1469-0691.2007.01716.x. Epub 2007 Apr 2. Clin Microbiol Infect. 2007. PMID: 17403131
-
The role of variable DNA tandem repeats in bacterial adaptation.FEMS Microbiol Rev. 2014 Jan;38(1):119-41. doi: 10.1111/1574-6976.12036. Epub 2013 Aug 28. FEMS Microbiol Rev. 2014. PMID: 23927439 Review.
-
Polymorphism of the human muc genes.Front Biosci. 2001 Oct 1;6:D1207-15. doi: 10.2741/A674. Front Biosci. 2001. PMID: 11578959 Review.
Cited by
-
Genetic diversity in Mycobacterium ulcerans isolates from Ghana revealed by a newly identified locus containing a variable number of tandem repeats.J Bacteriol. 2006 Feb;188(4):1462-5. doi: 10.1128/JB.188.4.1462-1465.2006. J Bacteriol. 2006. PMID: 16452429 Free PMC article.
-
Single nucleotide polymorphisms on the road to strain differentiation in Mycobacterium ulcerans.J Clin Microbiol. 2009 Nov;47(11):3647-52. doi: 10.1128/JCM.00761-09. Epub 2009 Sep 2. J Clin Microbiol. 2009. PMID: 19726608 Free PMC article.
-
Nineteen cases of Buruli ulcer diagnosed in Japan from 1980 to 2010.J Clin Microbiol. 2011 Nov;49(11):3829-36. doi: 10.1128/JCM.00783-11. Epub 2011 Aug 31. J Clin Microbiol. 2011. PMID: 21880966 Free PMC article.
-
Source tracking Mycobacterium ulcerans infections in the Ashanti region, Ghana.PLoS Negl Trop Dis. 2015 Jan 22;9(1):e0003437. doi: 10.1371/journal.pntd.0003437. eCollection 2015 Jan. PLoS Negl Trop Dis. 2015. PMID: 25612300 Free PMC article.
-
Distribution and Risk of Mycolactone-Producing Mycobacteria Transmission within Buruli Ulcer Endemic Communities in Côte d'Ivoire.Trop Med Infect Dis. 2017 Feb 26;2(1):3. doi: 10.3390/tropicalmed2010003. Trop Med Infect Dis. 2017. PMID: 30270862 Free PMC article.
References
-
- Asiedu, K., R. Scherpbier, and M. Raviglione. 2000. Executive summary, p. 1-4. In W.H.O./CDS/CPE/GBUI/2000.1. Buruli ulcer infection: Mycobacterium ulcerans infection. World Health Organization, Geneva, Switzerland.
-
- Chemlal, K., K. de Ridder, P. A. Fonteyne, W. M. Meyers, J. Swings, and F. Portaels. 2001. The use of IS2404 restriction fragment length polymorphisms suggests the diversity of Mycobacterium ulcerans from different geographic areas. Am. J. Trop. Med. Hyg. 64:270-273. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources