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Comparative Study
. 2005 Oct;43(10):5281-4.
doi: 10.1128/JCM.43.10.5281-5284.2005.

Comparative nucleotide sequence analysis of polymorphic variable-number tandem-repeat Loci in Mycobacterium ulcerans

Anthony Ablordey  1 , Markus Hilty, Pieter Stragier, Jean Swings, Françoise Portaels
Affiliations
Comparative Study

Comparative nucleotide sequence analysis of polymorphic variable-number tandem-repeat Loci in Mycobacterium ulcerans

Anthony Ablordey et al. J Clin Microbiol. 2005 Oct.

Abstract

We analyzed a set of variable-number tandem-repeat (VNTR) loci to assess their nucleotide sequence diversity in isolates of three Mycobacterium ulcerans genotypes. Sequence variants in two loci resulted in intraspecies resolution of Southeast Asian and Asian genotypes in contrast to a homogenous sequence composition among African isolates. Nucleotide sequence polymorphism in repeat units can enhance discrimination of VNTR loci.

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References

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