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. 2005 Oct;12(10):1235-7.
doi: 10.1128/CDLI.12.10.1235-1237.2005.

Immunoglobulin A antibody responses in dengue patients: a useful marker for serodiagnosis of dengue virus infection

M Nawa  1 , T Takasaki, M Ito, S Inoue, K Morita, I Kurane
Affiliations

Immunoglobulin A antibody responses in dengue patients: a useful marker for serodiagnosis of dengue virus infection

M Nawa et al. Clin Diagn Lab Immunol. 2005 Oct.

Abstract

We determined the usefulness of an immunoglobulin A (IgA) antibody-capture enzyme-linked immunosorbent assay for serodiagnosis of dengue virus infections. The results indicate that the presence of IgA and IgM in serum samples assures recent primary dengue virus infection even with a single serum sample.

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Figures

FIG. 1.
FIG. 1.
Detection of dengue virus-specific IgA (A) and IgM (B) on specific disease days. Closed and open columns indicate positive and negative, respectively.
FIG. 2.
FIG. 2.
Virus specificities of IgA and IgM antibodies among dengue and JE patients in Japan. Thirty-one serum samples (A and B) from 26 dengue patients and 22 (C and D) from 22 JE patients were subjected to IgA-capture ELISA (A and C) or IgM-capture ELISA (B and D). Results are presented as P/N ratios.
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