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Review
. 2005:125:1-16.
doi: 10.1007/0-387-24199-x_1.

Anatomy and physiology of the leptomeninges and CSF space

Neil Barshes  1 , Alexis Demopoulos, Herbert H Engelhard
Affiliations
Review

Anatomy and physiology of the leptomeninges and CSF space

Neil Barshes et al. Cancer Treat Res. 2005.

Abstract

The arachnoid membrane and pia mater are the two membranous layers that comprise the leptomeninges. Cerebrospinal fluid is made within the ventricular system by cells of the choroid plexus and ependyma. This chapter describes in detail the normal anatomic structure and physiologic interactions of the cerebrospinal fluid and leptomeningeal space that are critical to our understanding and treatment of leptomeningeal metastases.

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