Alternative splicing--when two's a crowd
- PMID: 16213205
- DOI: 10.1016/j.cell.2005.09.010
Alternative splicing--when two's a crowd
Abstract
Various mechanisms have been proposed to explain mutually exclusive splicing of pairs of exons. A paper in this issue of Cell (Graveley, 2005) provides a fascinating insight into the perplexing question of how only one exon at a time is chosen from an array of 48 exons in the Drosophila Dscam gene.
Comment on
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Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures.Cell. 2005 Oct 7;123(1):65-73. doi: 10.1016/j.cell.2005.07.028. Cell. 2005. PMID: 16213213 Free PMC article.
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