Telling the liver (not) to make bile acids: a new voice from the gut?
- PMID: 16213221
- DOI: 10.1016/j.cmet.2005.09.004
Telling the liver (not) to make bile acids: a new voice from the gut?
Abstract
The maintenance of adequate amounts of bile acids in the liver, biliary tract, and intestine requires a finely tuned control of their synthesis. A paper in this issue of Cell Metabolism by Inagaki et al. (2005) indicates that sensing of the levels of bile acids in the intestine may trigger the secretion of a hormone which regulates bile acid production in the liver.
Comment on
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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.Cell Metab. 2005 Oct;2(4):217-25. doi: 10.1016/j.cmet.2005.09.001. Cell Metab. 2005. PMID: 16213224
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