Resistance of Peptostreptococcus spp. to macrolides and lincosamides: inducible and constitutive phenotypes
- PMID: 1622181
- PMCID: PMC190575
- DOI: 10.1128/AAC.36.3.662
Resistance of Peptostreptococcus spp. to macrolides and lincosamides: inducible and constitutive phenotypes
Abstract
The activities of erythromycin and clindamycin against 350 Peptostreptococcus strains were studied during a 5-year period (1986 to 1991). In 5.1% of the Peptostreptococcus strains, which presented dissociated resistance (clindamycin MIC, less than or equal to 1 microgram/ml; erythromycin MIC, greater than 8 micrograms/ml), evidence of inducible macrolide-lincosamide resistance was shown. A total of 17.7% of the strains presented a constitutive phenotype; the clindamycin and erythromycin MICs for these strains were greater than 8 micrograms/ml.
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