Molecular adsorbent recirculating system--MARS as a bridge to liver transplantation in amanita phalloides intoxication

Abstract

A case of a 46-year-old female intoxicated with Amanita phalloides was presented. Since constant deterioration of her liver function she was put on the waiting list for urgent liver transplantation. To improve her clinical condition two sessions of Molecular Adsorbent Recirculating System were provided with transient good results. About 72 hours after the mushroom ingestion the patient had undergone liver transplantation.

Conclusions: Despite good clinical condition the patients severely poisoned with Amanita phalloides should be placed on a waiting list for liver transplantation as early as possible. The Molecular Adsorbent Recirculating System should be introduced as soon as possible after Amanita phalloides intoxication. Albumin dialysis may be considered as a bridge for the liver transplantation in patients intoxicated with Amanita phalloides.