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Review
. 2005 Dec;17(6):601-8.
doi: 10.1016/j.coi.2005.09.013. Epub 2005 Oct 13.

Genetic susceptibility to type 1 diabetes

Lisa M Maier  1 , Linda S Wicker
Affiliations
Review

Genetic susceptibility to type 1 diabetes

Lisa M Maier et al. Curr Opin Immunol. 2005 Dec.

Abstract

The recent discovery of PTPN22 as a novel susceptibility gene in human type 1 diabetes and continued progress in defining genes in animal models of the disease mark a fruitful period in the field of type 1 diabetes genetics. In addition, the similarities of the genetic and functional aspects across species have been substantiated. Future genome-wide association studies will reveal more loci, each providing a piece to the genetic puzzle of autoimmune disease.

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