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Case Reports
. 2005 Oct;140(4):757-8.
doi: 10.1016/j.ajo.2005.04.042.

Optical coherence tomography findings in tamoxifen retinopathy

Affiliations
Case Reports

Optical coherence tomography findings in tamoxifen retinopathy

Vincent Gualino et al. Am J Ophthalmol. 2005 Oct.

Abstract

Purpose: To describe optical coherence tomography (OCT) findings in two cases of typical tamoxifen retinopathy.

Design: Observational cases report.

Methods: Two patients with tamoxifen retinopathy were imaged with fluorescein angiography and OCT 3.

Results: Fluorescein angiography showed foveolar hyperfluorescence. OCT revealed a foveolar cystoid space with focal disruption of the photoreceptor line. There was no evidence of macular edema or thickening.

Conclusions: In both cases, OCT findings are not consistent with previous descriptions of tamoxifen retinopathy, based on fundus examination and fluorescein angiography, which include a description of macular edema. This new imaging suggests that tamoxifen maculopathy may include a foveolar cystoid space different from macular edema.

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